Research Interests:

Link to Coughlan Publication List

Recent Publications:

• Spavero, L.J., Patz, S., Brodsky, J.L., and Coughlan, C.M. (2007) Proteomic analysis of the Amyloid Precursor Protein fragment C99: Expression in Yeast. Anal. Biochem. 370:162-170 (DOI: 10.1016/j.ab.2007.07.033)
• Coughlan, C.M., and Brodsky, J.L. (2005). Use of yeast as a model system to investigate protein conformational diseases. Mol. Biotechnol. 30(2):171-180. (invited publication) (DOI: 10.1385/MB:30:2:171)
• Coughlan, C.M, Walker, J., Cochran, J., Wittrup, D. and Brodsky, J.L. (2004) Degradation of mutated bovine pancreatic trypsin inhibitor (BPTI) in the yeast vacuole suggests post endoplasmic reticulum protein quality control. J. Biol. Chem. 279(15):15289-15297 (DOI: 10.1074/jbc.M309673200)
• Coughlan, C.M and Brodsky, J.L (2003) The use of yeast as a model system to investigate protein conformational diseases. Methods in Molecular Biol. 232:77-90
• Chalasani. S.H., Baribaud. F., Coughlan. C.M., Lee. V.M.Y., Doms, R.W. and Raper. J.A. (2003( The chemokine SDF promotes the survival of embryonic retinal ganglion cells. J. Neurosci. 23(11):4601-4612
• Puffer, B.A., Sharron, M.P., Coughlan, C.M., Baribaud, F., McManus, C.M., Lee. B., David. J., Price. K., Horuk, R., Tsang, M., and Doms, R.W. (2000). Expression and coreceptor function of APJ for primate immunodeficiency viruses. Virology 276(2):435-444 (DOI: 10.1006/viro.2000.0557)